SYNTHESIS OF SOME N-OXIDES OF PYRIDYLACETHYLENE AMINES BASED ON 2-METHYL-5-ETHYNYLPYRIDINE

Authors

Abduvakhab IKRAMOV, Tashkent Chemical-Technological Institute, UzbekistanFollow
Odiljon ZIYADULLAYEV, Tashkent Chemical-Technological Institute, Tashkent, UzbekistanFollow
Adkham KHAMIDJANOV, Tashkent Chemical-Technological InstituteFollow
Shavkat BOJARIEV, Tashkent Chemical-Technological InstituteFollow
Davron KHANDAMOV, Tashkent Chemical-Technological InstituteFollow

DOI

10.51348/LUPI3276

Abstract

The aim of this work is to study the reaction of 2-methyl-5-ethynylpyridine N-oxide with some aliphatic and aromatic amines to obtain N-oxides of pyridylacetylenic amines. 2-Methyl-5-ethylpyridine converted to 2-methyl-5-vinylpyridine by dehydrogenation, and 2-methyl-5-ethynylpyridine obtained by bromination and dehydrobromination. 2-methyl-5-ethynylpyridine N-oxide synthesized by oxidation of 2-methyl-5-ethynylpyridine with perhydrol in acetic anhydride. The synthesis of N-oxides of pyridylacetylenic amines by the Mannich reaction carried out. The effect of the solvents: methanol, ethanol and n-dioxane, the catalyst, and the reaction time on the yield of the final product studied. The structure and composition of the synthesized PAA N-oxides were established using IR and PMR spectroscopy.

Recommended Citation

IKRAMOV, Abduvakhab; ZIYADULLAYEV, Odiljon; KHAMIDJANOV, Adkham; BOJARIEV, Shavkat; and KHANDAMOV, Davron (2021) "SYNTHESIS OF SOME N-OXIDES OF PYRIDYLACETHYLENE AMINES BASED ON 2-METHYL-5-ETHYNYLPYRIDINE," CHEMISTRY AND CHEMICAL ENGINEERING: Vol. 2021: No. 1, Article 9.
DOI: 10.51348/LUPI3276
Available at: https://cce.researchcommons.org/journal/vol2021/iss1/9