O-XLORATSETILTIMOL SINTEZI VA UNI KIMYOVIY MODIFIKATSIYALASH

Authors

Azimjon U. CHORIEV, Karshi State University, Karshi, UzbekistanFollow
Anvar K. ABDUSHUKUROV, National University of Uzbekistan, Tashkent, UzbekistanFollow
Ilyos U. NORMURODOV, Shakhrisabz branch of Tashkent institute of Chemical Technology, Shakhrisabz, UzbekistanFollow
Sarvinoz K. MIRZAYEVA, Karshi State University, Karshi, UzbekistanFollow

Abstract

The aim of the study is to develop a convenient method for the synthesis of O-chloroacetylthymol and to propose the mechanism of the O-chloroacetylation reaction. Thin-layer chromatography of chloroacetylation and nucleophilic substitution reaction products was studied and their composition was confirmed by reference substances. Nucleophilic exchange reactions of O-chloroacetylthymol with sodium oxalate, sodium tartrate, potassium rhodanides were studied. Favorable conditions for carrying out the nucleophilic exchange reaction were searched and 3 new substances unknown in the literature were synthesized. The structure of the synthesized substances was proved by IR and NMR spectra.

Recommended Citation

CHORIEV, Azimjon U.; ABDUSHUKUROV, Anvar K.; NORMURODOV, Ilyos U.; and MIRZAYEVA, Sarvinoz K. (2024) "O-XLORATSETILTIMOL SINTEZI VA UNI KIMYOVIY MODIFIKATSIYALASH," CHEMISTRY AND CHEMICAL ENGINEERING: Vol. 2024: No. 3, Article 5.
DOI: https://doi.org/10.34920/cce202435
Available at: https://cce.researchcommons.org/journal/vol2024/iss3/5