TECHNOLOGY OF OBTAINING A FOOD ADDITIVE FROM CITRULLUS COLOCYNTHIS AND ITS HYPOGLYCEMIC ACTIVITY

Authors

Isomiddin BOBAEV, Tashkent Chemical-Technological InstituteFollow
Маrkhаbоkhон MAKHMUDOVA, Institute of the Chemistry of Plant SubstancesFollow
Khayrulla BOBAKULOV, Institute of the Chemistry of Plant SubstancesFollow
Vladimir SYROV, Institute of the Chemistry of Plant SubstancesFollow
Nasrulla ABDULLAEV, Institute of the Chemistry of Plant SubstancesFollow

Abstract

The aim of the study is to develop a technology for obtaining a food additive for the extract of the pulp of bitter watermelon - Citrullus colocynthis, introduced in Uzbekistan as a hypoglycemic agent. Pharmacological studies have shown the presence of a hypoglycemic effect for aqueous and alcoholic extracts and 2-O-β-glucopyranosyl-cucurbitacin E in rats with alloxan diabetes mellitus. Cucurbitacins were isolated from the extract - cucurbitacin E, 2-O-β-glucopyranosyl-cucurbitacin E and other bioactive substances.

The food supplement obtained from bitter watermelon (Citrullus colocynthis (family Cucurbitaceae)) according to the developed technology showed a higher hypoglycemic activity compared to the drug arfazetin.

Recommended Citation

BOBAEV, Isomiddin; MAKHMUDOVA, Маrkhаbоkhон; BOBAKULOV, Khayrulla; SYROV, Vladimir; and ABDULLAEV, Nasrulla (2021) "TECHNOLOGY OF OBTAINING A FOOD ADDITIVE FROM CITRULLUS COLOCYNTHIS AND ITS HYPOGLYCEMIC ACTIVITY," CHEMISTRY AND CHEMICAL ENGINEERING: Vol. 2021: No. 1, Article 13.
DOI: https://doi.org/10.51348/TXGZ2036
Available at: https://cce.researchcommons.org/journal/vol2021/iss1/13