SYNTHESIS OF AROMATIC ACETYLENE ALCOHOLS USING COMPLEX CATALYTIC SYSTEMS

Authors

Odiljon ZIYADULLAEV, Chirchik State Pedagogical Institute, Chirchik, UzbekistanFollow
Guzal OTAMUKHAMEDOVA, Chirchik State Pedagogical Institute, Chirchik, UzbekistanFollow
Abduvakhab IKRAMOV, Tashkent Chemical-Technological Institute,Tashkent, UzbekistanFollow
Saida ABDURAKHMANOVA, Tashkent Chemical-Technological Institute, Tashkent, UzbekistanFollow
Otabek BOYTEMIROV, Chirchik state pedagogical institute, Chirchik, UzbekistanFollow

Abstract

Some cyclic ketones (cyclopentanone, cyclohexanone, 2-methylcyclohexanone, menthol, camphor and adamantanone) enantioselective alkynylation reactions with phenylacetylene have been studied in the presence of complex catalytic systems - Zn(OTf)₂/NЕt₃/MeCN, 3,3′-Ph₂BINOL-2Li/TGF and BuLi/KO^tBu/TGF. Synthesis were performed new aromatic acetylene alcohols – 1-(2-phenylathinyl) cyclopentanol (1), 1-(2-phenylethinyl)cyclohexanol (2), 2-methyl-1-(2-phenylethinyl)cyclohexanol (3), 2-isopropyl-5-methyl-1-(2-phenylethinyl)cyclohexanol (4), 1,7,7,-trimethyl-2-(2-phenylethinyl)bicyclo [2.2.1] heptanol-2 (5) and 2-phenylethinyltricyclo [3,3,1.0^3,7]nonanol-2 (6). Synthesis reactions of aromatic acetylene alcohols, activation energies were determined, kinetic of chemical changes and reaction mechanisms were proposed. The course of the reactions and the effect of the selected ketone molecule size, structure and number of rings on the product yield have analyzed. A series of catalytic activity of the applied complex catalytic systems has developed.

Recommended Citation

ZIYADULLAEV, Odiljon; OTAMUKHAMEDOVA, Guzal; IKRAMOV, Abduvakhab; ABDURAKHMANOVA, Saida; and BOYTEMIROV, Otabek (2021) "SYNTHESIS OF AROMATIC ACETYLENE ALCOHOLS USING COMPLEX CATALYTIC SYSTEMS," CHEMISTRY AND CHEMICAL ENGINEERING: Vol. 2021: No. 2, Article 6.
DOI: https://doi.org/10.51348/ZYJH5048
Available at: https://cce.researchcommons.org/journal/vol2021/iss2/6